Cabergoline Tablets: A Balanced Look at Effectiveness and Safety

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Cabergoline should be used with caution in patients with hepatic disease.

Cabergoline is a safe and effective treatment option for postpartum women who want to or need to suppress prolactin levels. However, it is important to weigh the potential side effects with its benefits.

Most medicines can cause unwanted side-effects. Tell your doctor and pharmacist if you experience them. These often improve as you get used to the medication.

Dosage and Administration

Cabergoline Tablets is taken by mouth, usually once or twice daily. The dosage is determined by your doctor, based on the condition being treated and your general health. Your doctor may start you on a low dose and gradually increase your dosage. Older adults (65 years and older) may have a slower response to this medication, and should be started on a low dose and increased slowly. If you take this medication with other medications that affect your prolactin levels, such as lorcaserin, metoclopramide, or others, talk to your doctor about possible interactions.

This medication should not be used during pregnancy, unless the benefits outweigh the risks. If you become pregnant while taking this medication, tell your doctor right away. Also, this medication passes into breast milk, so be sure to discuss breastfeeding with your doctor before starting treatment.

Most medicines cause unwanted side effects, and some of these can be serious. Your doctor will explain which side effects to expect and how they may improve as your body adjusts to the drug.

Rarely, cabergoline can damage your heart valves. Your doctor will listen to your heart and may perform an echocardiogram before starting treatment, and will repeat the scan if you need long-term therapy. Your doctor may also want to monitor your blood pressure, lung function, and X-rays from time to time while you are taking this medication.

Side Effects

Some people who take Cabergoline may have a side effect called atypical impulsive behaviour. It includes intense urges such as a strong desire to gamble and increased sexual desires, which are hard to control. These effects usually settle when treatment is stopped. It's worth letting your family and friends know about this risk, so they can call you if they notice changes in your behaviour.

Taking Cabergoline tablets with food can reduce some of these side effects. Dizziness can also be a side effect, so it's important to get up from a chair or bed slowly to avoid falls. To help prevent this, dangle your feet on the edge of the bed or pause for a few seconds before standing up. This will allow your blood pressure to stabilize before you stand up.

In some cases, high doses of cabergoline can cause problems with heart valves, a rare condition known as valvular disease. In this case, your doctor will order regular echocardiograms to monitor your heart health while you take the medication.

It's also a good idea to tell your doctor about any other medical conditions you have, such as liver problems or pregnancy. Women who are pregnant or plan to become pregnant should not take this medication unless it's absolutely necessary and the benefits outweigh the risks.

Precautions

Cabergoline can cause a number of side effects, such as dizziness and fatigue. These may be mild and go away on their own or with treatment. If these symptoms are severe or do not go away, contact your doctor. In some cases, long-term use of this medication can lead to heart valve problems. Your doctor will listen to your heart and arrange for an echocardiogram (echo) heart scan before starting treatment and may repeat the test during long-term therapy.

Taking this medication with other drugs can increase your risk of adverse side effects. Talk to your doctor about what other medications you are taking, including vitamins and herbs. Cabergoline can interact with some medications, such as antipsychotics, lorcaserin and metoclopramide. It is also known to interact with clozapine and other benzodiazepines.

Cabergoline should not be used during pregnancy unless it is clearly needed. Studies have not shown a positive effect on the unborn baby, and it can be excreted into breast milk. Nursing women should discuss this with their doctor.

Rarely, this medicine can cause changes in behavior, such as aggressive behaviour, hostility or hallucinations. These changes may be more likely in people who have a history of mental illness or who take certain other drugs, such as antipsychotics or antidepressants. The risk of these changes is higher in older adults.

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Overdose

Unless otherwise directed, a dose of Cabergoline should not be taken more than once in 24 hours. The drug should not be given to children under the age of 16 unless specifically recommended by your doctor. This medication can cause drowsiness. It is important to avoid driving and operating machinery until you know how this medicine affects you. Cabergoline can also lower your blood pressure, so be careful getting up from a sitting or lying position. This can increase your risk of falling down, which could lead to serious injury or death.

Rarely, Cabergoline may cause psychiatric disturbances such as abnormally impulsive behaviour (e.g. strong urge to gamble or a greatly increased sex drive). If this happens, let your doctor and close relatives know about it. The onset of such effects is usually in the first month or two of treatment and will settle when treatment is stopped.

Cabergoline should be used with caution in patients with hepatic disease, liver cancer or cirrhosis, Raynaud's syndrome, severe cardiovascular diseases, peptic ulcer or gastrointestinal bleeding and with history of psychotic disorder. Long-term treatment with the drug has been associated with cardiac valvulopathy and should be avoided in such patients.

 

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